Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

1.5K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.5K
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

23
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
23
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

13
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
13
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

146
Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
146
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

17
Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
17
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

38
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
38

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lifetime management of aortic stenosis: A primer for the generalist.

The American journal of medicine·2026
Same author

Longitudinal analysis of explosive physical performance outcomes of professional athletes across multiple football codes: An investigation of systematic change and relative variation.

Journal of sports sciences·2026
Same author

Outcomes of a UK day case shoulder arthroplasty pathway: Safety, patient satisfaction and cost-saving analysis.

Shoulder & elbow·2026
Same author

The right kind of rarefaction: Coronary microvascular remodeling in right ventricle failure.

JHLT open·2026
Same author

ASO Visual Abstract: Surgical Management and Outcomes in Pediatric Adrenocortical Carcinoma: A Pediatric Surgical Oncology Research Collaborative Study.

Annals of surgical oncology·2025
Same author

Divergent Responses to Training Load in Professional Australian Football: Are Insights Obtained from Generic and Running-based Assessments Complementary or Redundant?

Sports medicine - open·2025

Related Experiment Video

Updated: Aug 29, 2025

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
09:37

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Published on: December 2, 2014

28.1K

Mechanical Complications of Myocardial Infarction.

Andrew Murphy1, Sheldon Goldberg1

  • 1Pennsylvania Hospital of the University of Pennsylvania Health System, Philadelphia.

The American Journal of Medicine
|September 8, 2022
PubMed
Summary

Mechanical complications after myocardial infarction, such as cardiac rupture, are now less common due to reperfusion therapies. Echocardiography is key for diagnosis, with surgery often needed for these serious heart conditions.

Keywords:
Cardiogenic shockFree wall ruptureMyocardial infarctionPapillary muscle ruptureVentricular septal rupture

More Related Videos

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice
09:05

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice

Published on: May 4, 2015

27.9K
Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.1K

Related Experiment Videos

Last Updated: Aug 29, 2025

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
09:37

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Published on: December 2, 2014

28.1K
Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice
09:05

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice

Published on: May 4, 2015

27.9K
Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.1K

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Medical Imaging

Background:

  • Mechanical complications, including cardiac rupture, are serious consequences of myocardial infarction.
  • The incidence of these complications has decreased with advancements in acute coronary reperfusion therapies.
  • Cardiogenic shock following myocardial infarction warrants suspicion for mechanical complications.

Purpose of the Study:

  • To review predictors, clinical features, diagnostic methods, and management strategies for mechanical complications of myocardial infarction.
  • To highlight the importance of early recognition and intervention.
  • To discuss the role of echocardiography and surgical repair.

Main Methods:

  • Review of literature on mechanical complications of myocardial infarction.
  • Analysis of diagnostic approaches, primarily echocardiography.
  • Evaluation of management strategies, including medical circulatory support and surgical repair.

Main Results:

  • Acute coronary reperfusion has significantly reduced the incidence of mechanical complications.
  • Echocardiography is the primary diagnostic tool for these complications.
  • Urgent surgical repair is often necessary, despite the role of mechanical circulatory support.

Conclusions:

  • Mechanical complications remain a critical concern post-myocardial infarction, necessitating high clinical suspicion.
  • Prompt diagnosis via echocardiography and timely surgical intervention are crucial for patient outcomes.
  • Continued research into predictors and optimal management strategies is warranted.