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Polymorphisms in the Genes Coding for TLRs, NLRs and RLRs Are Associated with Clinical Parameters of Patients with

Katarzyna Wicherska-Pawłowska1, Katarzyna Bogunia-Kubik2, Bartłomiej Kuszczak1

  • 1Department and Clinic of Hematology, Blood Neoplasms and Bone Marrow Transplantation of Wroclaw Medical University, 50-367 Wroclaw, Poland.

International Journal of Molecular Sciences
|September 9, 2022
PubMed

Keywords:
acute myeloid leukemiainnate immunitysingle-nucleotide polymorphisms

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
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