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Mechanism of inhibition of junctional communication between animal cells by phorbol ester
Cell and Tissue Kinetics
|March 1, 1987
Abstract:
The tumour promotor 4 beta-phorbol 12-myristate 13-acetate (TPA) reduces the rate of junction formation between V79 Chinese hamster lung cells in culture but not between BHK21/13 Syrian hamster fibroblasts. TPA may act on all cells but only affect junction formation in those situations where the rate of junction formation is already low.