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Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
Published on: September 15, 2023
890
Lateral Involvement in Different Sized Papillary Thyroid Carcinomas Patients with Central Lymph Node Metastasis: A
Yu Heng1, Zheyu Yang2, Pengyu Cao1
1ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Journal of Clinical Medicine
|September 9, 2022
Summary
This study developed a risk stratification tool to predict lateral lymph node metastasis in papillary thyroid cancer patients with central lymph node metastasis. The tool helps guide postoperative treatment decisions for better patient outcomes.
Area of Science:
- Oncology
- Surgical Oncology
- Endocrine Surgery
Background:
- Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer.
- Central lymph node metastasis (CLNM) is a common finding in PTC.
- Predicting lateral lymph node metastasis (LLNM) is crucial for guiding postoperative adjuvant treatment.
Purpose of the Study:
- To quantitatively predict the probability of LLNM in PTC patients with CLNM.
- To guide postoperative adjuvant treatment decisions.
Main Methods:
- Retrospective analysis of 503 PTC patients with CLNM from three medical centers.
- Identification of independent risk factors for LLNM in papillary thyroid microcarcinoma (PTMC) and large papillary thyroid carcinoma (LPTC).
- Development and validation of predictive nomograms and a risk stratification flowchart.
Main Results:
- The overall LLNM rate was 23.9%.
- Risk factors for LLNM varied between PTMC and LPTC.
- Established predictive nomograms and a risk stratification flowchart demonstrated accuracy and validity.
Conclusions:
- A detailed risk stratification flowchart for PTC patients with CLNM was established.
- This tool aids in quantitatively assessing LLNM risk.
- The flowchart can assist in clinical decision-making for postoperative adjuvant treatment.
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