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The Oscillometric Pulse Wave Analysis Is Useful in Evaluating the Arterial Stiffness of Obese Children with Relevant

Monica Simina Mihuta1, Corina Paul2, Andreea Borlea3

  • 1Department of Doctoral Studies, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.

Journal of Clinical Medicine
|September 9, 2022
PubMed

Insights

Childhood obesity increases arterial stiffness and blood pressure. Pulse wave analysis (PWA) in obese children reveals that factors like risky pregnancy and smoking worsen these vascular effects, highlighting the need for early detection.

Area of Science:

  • Pediatrics
  • Cardiology
  • Public Health

Background:

  • Childhood obesity is a growing concern linked to vascular complications.
  • Early detection of these complications is crucial for effective management.
  • Obesity can lead to increased arterial stiffness and elevated blood pressure in children.

Purpose of the Study:

  • To evaluate the reliability of pulse wave analysis (PWA) in assessing vascular health in obese children.
  • To investigate the influence of additional risk factors on PWA parameters and blood pressure in this population.

Main Methods:

  • A study involving 55 children (6-18 years old), divided into obese (n=30) and normal-weight (n=25) groups.
  • Measurements included pulse wave velocity (PWV), augmentation index (AIx), peripheral and central blood pressure, and heart rate using the IEM Mobil-O-Graph.
  • Clinical and anamnestic assessments were performed, focusing on risk factors like pregnancy history, smoking, sleep, and physical activity.

Main Results:

  • Body Mass Index (BMI) and waist circumference significantly correlated with higher PWV, SBP, DBP, cSBP, and cDBP.
  • Weight was a significant predictor of PWV, SBP, DBP, and cPP.
  • Risk factors such as cardiometabolically risky pregnancy, smoking, sleep deprivation, and sedentariness were associated with elevated vascular parameters.

Conclusions:

  • Pulse wave analysis is a reliable tool for assessing arterial stiffness and blood pressure in obese children.
  • Obese children with additional cardiometabolic risk factors exhibit significantly increased arterial stiffness and blood pressure.
  • Early identification and management of risk factors are essential to mitigate vascular complications in childhood obesity.

Keywords:
arterial stiffnesscardiometabolic riskchildhood obesityhigh blood pressurepulse wave analysis

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