Related Experiment Video

Updated: Aug 29, 2025

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
08:18

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model

Published on: February 8, 2022

2.5K

Lobar intracerebral hemorrhage and risk of subsequent uncontrolled blood pressure

Evangelos Pavlos Myserlis1,2,3,4, Ernst Mayerhofer1,2,3,4, Jessica R Abramson1,2,3,4

  • 1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.

European Stroke Journal
|September 9, 2022
PubMed

Insights

Intracerebral hemorrhage (ICH) survivors with lobar bleeds had higher rates of uncontrolled blood pressure (BP). This was linked to fewer antihypertensive medications, not the bleed location itself.

Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • Uncontrolled blood pressure (BP) is prevalent in intracerebral hemorrhage (ICH) survivors, correlating with poor clinical outcomes.
  • The relationship between ICH characteristics and sustained uncontrolled BP requires further investigation.

Purpose of the Study:

  • To determine if specific intracerebral hemorrhage (ICH) characteristics are associated with uncontrolled blood pressure (BP) at 6-month follow-up.
  • To analyze the impact of hematoma location and volume on post-ICH BP control.

Main Methods:

  • Prospective longitudinal study of 1492 primary ICH survivors (age ≥18) from 1994-2015.
  • Assessed uncontrolled BP (mean BP ≥140/90 mmHg) at 6 months post-ICH.
  • Used multivariable logistic regression to evaluate hematoma location, volume, and event year effects on uncontrolled BP.

Main Results:

  • Lobar ICH location was initially associated with a higher risk of uncontrolled BP at 6 months (OR 1.35).
  • Lobar ICH survivors received fewer antihypertensive drugs compared to other groups.
  • After adjusting for medication, the association between lobar ICH and uncontrolled BP was no longer significant.

Conclusions:

  • ICH survivors with lobar hemorrhages were more likely to have uncontrolled BP, primarily due to reduced antihypertensive medication.
  • Future strategies should prioritize aggressive BP management post-ICH, irrespective of hemorrhage location.
Abstract

Keywords:
Blood pressureHypertensionIntracerebral hemorrhageStroke

More Related Videos

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

2.5K
Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation09:01

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Published on: October 15, 2021

7.8K

Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
2.3K
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
57
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
1.3K
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
1.7K
The Arch of Aorta01:10

The Arch of Aorta

The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
957
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
1.2K