Application value of Qisexingtai hand diagnostic method in diagnosis of coronary artery disease
Related Experiment Video
Updated: Aug 29, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Liu Qian1, Zhao Zhupei1, Guo Hua2
1Institute for the History of Chinese Medicine and Medical Literature, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Insights
The Qisexingtai hand diagnostic method shows promise for diagnosing coronary artery disease (CAD), demonstrating high accuracy and sensitivity in a multi-center study. This traditional method offers a valuable complementary approach for CAD assessment.
Area of Science:
- Cardiology
- Diagnostic Medicine
- Traditional Chinese Medicine
Background:
- Coronary artery disease (CAD) poses a significant global health challenge.
- Accurate and accessible diagnostic methods are crucial for timely intervention.
- The Qisexingtai hand diagnostic method, rooted in traditional practices, warrants investigation for its clinical utility in CAD detection.
Purpose of the Study:
- To evaluate the diagnostic efficacy of the Qisexingtai hand diagnostic method for coronary artery disease (CAD).
- To compare the Qisexingtai method's performance against coronary angiography, the gold standard.
Main Methods:
- A prospective, multi-center, cross-sectional study involving 326 participants.
- Participants underwent diagnosis using both the Qisexingtai hand method and coronary angiography.
- Key performance metrics including sensitivity, specificity, and accuracy were calculated.
Main Results:
- The Qisexingtai hand diagnostic method achieved a sensitivity of 80.2% and a specificity of 68.7%.
- The overall accuracy of the Qisexingtai method was 73.3%, with an area under the ROC curve of 0.735.
- The omission diagnostic rate was 19.8%, and the mistaken diagnostic rate was 31.3%.
Conclusions:
- The Qisexingtai hand diagnostic method demonstrates considerable accuracy and sensitivity in diagnosing CAD.
- This traditional diagnostic approach holds potential value as an adjunct tool for CAD assessment.
Objective:
To evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method in the diagnosis of coronary artery disease (CAD).
Methods:
This was an investigator-initiated, prospective, multi-center, cross-sectional study. All the participants from three hospitals in China had been diagnosed by both Qisexingtai hand diagnostic method and coronary angiography. We compared the two diagnostic methods to calculate the sensitivity, the specificity, the omission diagnostic rate, the mistaken diagnostic rate and accuracy in order to evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method for CAD.
Results:
A total of 326 subjects were enrolled, diagnosed by both Qisexingtai hand diagnostic method and coronary angiography. As a result, there were 166 positive cases according to Qisexingtai hand diagnostic method, and 131 positive cases according to coronary angiography. Compared with the results of coronary angiography, the sensitivity of Qisexingtai hand dia-gnostic method was 80.2%, the specificity was 68.7%, the omission diagnostic rate was 19.8%, the mistaken diagnostic rate was 31.3%, and the accuracy was 73.3%. Area under the receiver operating characteristic curve was estimated as 0.735 for all, and 0.718, 0.735, 0.783 for the three sub-centers.
Conclusion:
Qisexingtai hand diagnostic method with high accuracy and sensitivity has certain application value in the diagnosis of CAD.
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