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Updated: Aug 29, 2025

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Initiating DNA-Encoded Library Synthesis with a Hexathymidine DNA Oligonucleotide

Mateja Klika Škopić1, Denise Dos Santos Smith1, Anne Gohla1

  • 1Department of Chemistry and Chemical Biology, TU Dortmund University, Dortmund, Germany.

Methods in Molecular Biology (Clifton, N.J.)
|September 9, 2022
PubMed

Keywords:
Adapter oligonucleotideAu(I)-mediated heterocycle synthesisDNA ligationDNA-encoded chemistryDNA-encoded libraryHexathymidinePictet-Spengler reactionSolid-phase synthesis

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