From real-time single to multicompartmental Hodgkin-Huxley neurons on FPGA for bio-hybrid systems

Modeling biological neural networks has been a field opening to major advances in our understanding of the mechanisms governing the functioning of the brain in normal and pathological conditions. The emergence of real-time neuromorphic platforms has been leading to a rising significance of bio-hybrid experiments as part of the development of neuromorphic biomedical devices such as neuroprosthesis. To provide a new tool for the neurological disorder characterization, we design real-time single and multicompartmental Hodgkin-Huxley neurons on FPGA. These neurons allow biological neural network emulation featuring improved accuracy through compartment modeling and show integration in bio-hybrid system thanks to its real-time dynamics.