Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A simple microcomputer program for predicting the secondary structure of proteins.

S Pascarella, F Bossa

    Computer Methods and Programs in Biomedicine
    |June 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Golimumab improves health-related quality of life of patients with moderate-to-severe ulcerative colitis: Results of the go-care study.

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2023
    Same author

    Evaluation of factors associated with trust in telemedicine in patients with inflammatory bowel disease during COVID-19 pandemic: a multicenter cross-sectional survey.

    European review for medical and pharmacological sciences·2022
    Same author

    Worse impact of second wave COVID-19 pandemic in adults but not in children with inflammatory bowel disease: an Italian single tertiary center experience.

    European review for medical and pharmacological sciences·2021
    Same author

    Azathioprine for prevention of clinical recurrence in Crohn's disease patients with severe endoscopic recurrence: an IG-IBD randomized double-blind trial.

    European review for medical and pharmacological sciences·2020
    Same author

    Breast Tumor Malignancy Classification using Smartphone Compression-induced Sensing System and Deformation Index Ratio.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2020
    Same author

    Mathematical model for preoperative identification of obstructed nasal subsites.

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2017
    Same journal

    Accounting for approximation errors using surrogate-based parameter estimation of cardiac mechanics digital twins.

    Computer methods and programs in biomedicine·2026
    Same journal

    Facial iPPG heatmap patterns based on period-aware autoencoder show association with carotid atherosclerosis towards non-contact hemodynamic assessment.

    Computer methods and programs in biomedicine·2026
    Same journal

    Explainable machine learning models predict liver fibrosis risk and outcome in the general population: Development and multi-cohort external validation.

    Computer methods and programs in biomedicine·2026
    Same journal

    Evaluation of surrogate endpoints for survival outcomes using the surrogate package in R.

    Computer methods and programs in biomedicine·2026
    Same journal

    Relative spectral and frication-based descriptors as numerical indicators of place of articulation shifts in fricatives produced by Polish children.

    Computer methods and programs in biomedicine·2026
    Same journal

    Leaflet resection improves valve expansion and hemodynamic performance in redo TAVI with balloon- and self-expanding transcatheter heart valve configurations.

    Computer methods and programs in biomedicine·2026
    See all related articles

    This study presents a BASIC program for protein secondary structure prediction using Chou-Fasman and Garnier-Osguthorpe-Robson rules. The software visualizes predictions, charge distribution, and consensus, aiding in protein structure analysis.

    Area of Science:

    • Biochemistry
    • Computational Biology
    • Bioinformatics

    Background:

    • Predicting protein secondary structure is crucial for understanding protein function.
    • Existing methods for secondary structure prediction have varying levels of accuracy.
    • Computational approaches offer efficient ways to analyze protein structures.

    Purpose of the Study:

    • To develop a user-friendly program for predicting protein secondary structure.
    • To implement established Chou-Fasman and Garnier-Osguthorpe-Robson algorithms.
    • To visualize prediction results, including charge distribution and consensus.

    Main Methods:

    • An Applesoft BASIC program was developed for the Apple IIe computer.
    • The program incorporates Chou-Fasman and Garnier-Osguthorpe-Robson algorithms.

    Related Experiment Videos

  • Results are visualized graphically and can be printed using an Imagewriter printer.

    • Main Results:

    • The program successfully applies Chou-Fasman and Garnier-Osguthorpe-Robson rules.
    • Visualizations include secondary structure predictions, charge distribution, and consensus predictions.
    • The software provides a practical tool for analyzing protein secondary structures.

    Conclusions:

    • The developed program offers a straightforward method for secondary structure prediction.
    • The visualization features enhance the interpretation of prediction results.
    • This tool can be valuable for researchers in protein science and bioinformatics.