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A BODIPY-based ICT probe for ratiometric and chromo-fluorogenic detection of hazardous oxalyl chloride
M Deniz Yilmaz1, Haluk Samet Kocak2, Hatice Kubra Kara3
1Department of Bioengineering, Faculty of Engineering and Architecture, Konya Food and Agriculture University (KFAU), 42080 Konya, Turkey; Research and Development Center for Diagnostic Kits (KIT-ARGEM), Konya Food and Agriculture University (KFAU), 42080 Konya, Turkey; Department of Materials Science and Nanotechnology, Graduate School of Natural and Applied Sciences, Konya Food and Agriculture University (KFAU), 42080 Konya, Turkey.
Abstract:
Herein, a novel long wavelength monostyryl BODIPY derivative (BDZ-1) has been synthesized by rational design and used to detect oxalyl chloride, a highly reactive and harmful chemical to humans and other living organisms, with high sensitivity and selectivity. The purple solution of BDZ-1 changed to pink color immediately upon the addition of oxalyl chloride and the weak red fluorescence changed to strong orange fluorescence simultaneously. In addition, the practicability of BDZ-1 was further explored by using a smartphone application, allowing the sensitive and selective on-site detection of oxalyl chloride.
