Volumetric Measurements Improve the Accuracy of Aortic Remodeling Prediction in Aortic Dissection

Accessing aortic remodeling status through regular follow-ups is essential for acute type A aortic dissection patients undergone surgical treatment. Aortic remodeling status was usually determined using diameter or area measurements of the true and false lumen in specific anatomical slices of medical images. However, these indicators only represent partial information about the aorta and can hardly characterize the overall aorta situation. In this study, we included two types of morphology features collected from computed tomography angiography images to predict the aortic remodeling. One type is the volumetric measurements of the true and false lumen, which provide a better overall description of the aorta, and the other type is the volumetric measurements of the thrombus in false lumen and the patent false lumen, which present more detailed information of the dissection. Through progressively incorporating these measurements into the construction of the remodeling prediction model, we investigated the importance of the features that describe the overall situation and that characterize aortic internal details in remodeling prediction, especially the effect of quantitative thrombosis features. The results showed that with the inclusion of the two types of volume features, the prediction accuracy of the model increased, which proves that volumetric measurements of aortic dissection, especially the volume of thrombus, are of significant value in aortic remodeling prediction, and should be paid more attention on in clinical practice and research areas. Clinical Relevance-Demonstrating the importance of volumetric measurements of true and false lumen thrombus in false lumen and patent false lumen in the prediction of aortic remodeling.