Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Routine terminal ileal intubation: reconsidering its role in screening colonoscopy.

Gastrointestinal endoscopy·2026

Same author

Reconsideration of the So-Called "Someya's Sinew String": An Anatomical Structure or a Postoperative Scar?

Clinical anatomy (New York, N.Y.)·2026

Same author

The Burden of Transthyretin Amyloid Cardiomyopathy on Caregivers and Patients in Japan: A Cross‑Sectional Real‑World Survey.

Advances in therapy·2026

Same author

Hospital-based gastric cancer outcomes in the United States (2003-2022): racial and regional disparities.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·2026

Same author

A soft diet attenuates exercise-induced increases in cortical bone density and formation in long bones in growing mice.

Scientific reports·2026

Same author

Gastric indefinite for dysplasia: from diagnostic uncertainty to risk-stratified management.

Gastrointestinal endoscopy·2026

Search research articles

Related Experiment Video

Updated: Aug 29, 2025

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

Reevaluation of Gastric Cancer Screening by Levin's Equation.

Naoki Ishii¹, Yasutoshi Shiratori², Takahiko Yano¹

¹Division of Gastroenterology, Tokyo Shinagawa Hospital, Tokyo, Japan.

Clinical and Translational Gastroenterology

|September 10, 2022

Summary

Gastric cancer screening using fluoroscopy and endoscopy shows decreasing effectiveness, particularly in women. Population-attributable risk calculations reveal a declining impact of these screening methods on gastric cancer mortality over time.

More Related Videos

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

Published on: May 10, 2024

Related Experiment Videos

Last Updated: Aug 29, 2025

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

Published on: May 10, 2024

Area of Science:

Oncology
Public Health
Epidemiology

Background:

Gastric cancer remains a significant global health concern.
Population-level screening strategies are crucial for reducing cancer mortality.
The long-term effectiveness of established screening methods requires ongoing evaluation.

Purpose of the Study:

To reevaluate the population-level effectiveness of fluoroscopy and endoscopy in reducing gastric cancer mortality.
To analyze trends in gastric cancer mortality rates in relation to screening introduction.
To quantify the population-attributable risk (PAR) of gastric cancer mortality associated with the absence of screening.

Main Methods:

Utilized Cancer Registry and Statistics data to extract gastric cancer mortality and screening introduction rates.
Applied Levin's equation to calculate the population-attributable risk (PAR) percent of no screening for gastric cancer mortality.
Employed Jonckheere-Terpstra test and linear regression to assess trends in PAR across different decades and demographics.

Main Results:

A significant decrease in the PAR of gastric cancer mortality was observed in the total, male, and female populations.
The PAR of crude mortality rates in females significantly decreased in 2000-2009 and 2010-2019 compared to 1980-1989.
The PAR of age-adjusted mortality rates showed significant decreases in both males and females in recent decades.

Conclusions:

Levin's equation effectively estimates the PAR of no screening for gastric cancer mortality.
The effectiveness of current gastric cancer screening methods (fluoroscopy and endoscopy) appears to be diminishing.
A notable decrease in screening effectiveness was particularly observed in the female population.