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Constant morphine infusion for severe sickle cell crisis pain
Drug Intelligence & Clinical Pharmacy
|July 1, 1987
Summary
Continuous intravenous morphine infusion effectively managed severe sickle cell crisis pain. This method provided rapid, safe analgesia when intermittent injections failed, offering a superior alternative for pain control.
Area of Science:
- Pain Management
- Hematology
- Pharmacology
Background:
- Severe sickle cell crisis often presents with intractable pain.
- Conventional intermittent narcotic injections may provide inadequate analgesia.
Observation:
- A patient with severe sickle cell crisis experienced poor pain control with standard intermittent opioid therapy.
- Continuous intravenous infusion of morphine sulfate was initiated.
Findings:
- Adequate pain relief was achieved within two hours of starting the morphine infusion.
- No adverse effects were observed during the continuous infusion therapy.
Implications:
- Continuous intravenous narcotic infusion offers an effective and safe alternative for managing sickle cell crisis pain.
- This protocol may improve patient outcomes compared to intermittent injection methods.