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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

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Overview
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Hypersensitivities01:30

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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Upper Respiratory Drugs: First and Second-Generation Antihistamines01:15

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Antihistamines are a class of drugs widely used to alleviate the symptoms of allergies, such as sneezing, itching, and nasal congestion. They work by inhibiting the actions of histamine, which is released by immune cells in response to allergenic substances or tissue injuries.
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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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Allergies and Natural Alternatives.

Walter M Jongbloed1, Seth M Brown1

  • 1Division of Otolaryngology, Department of Surgery, University of Connecticut, School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA.

Otolaryngologic Clinics of North America
|September 10, 2022
PubMed
Summary
This summary is machine-generated.

Complementary and integrative medicine offers options for allergy and allergic rhinitis (AR) treatment, with varying safety and efficacy. Manuka honey, butterbur, and Sinupret show the most promise for AR symptom relief.

Keywords:
Allergic rhinitisAllergy treatmentComplementary medicineIntegrative medicine

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Area of Science:

  • Integrative medicine
  • Allergy research
  • Complementary therapies

Background:

  • Allergic rhinitis (AR) management includes complementary and integrative medicine.
  • Therapies range from nutritional and herbal supplements to Ayurvedic and traditional Chinese medicine.
  • Safety and efficacy of these treatments are not well-established.

Purpose of the Study:

  • To review complementary and integrative medicine therapies for allergy and allergic rhinitis.
  • To assess the safety and evidence base for various treatments.
  • To identify therapies with the strongest supporting evidence.

Main Methods:

  • Literature review of complementary and integrative medicine for AR.
  • Categorization of therapies into nutritional, herbal, Ayurvedic, and traditional Chinese medicine.
  • Evaluation of safety profiles and existing research on efficacy.

Main Results:

  • Therapies include Manuka honey, butterbur, and Sinupret, with varied safety and research.
  • Some therapies, like ephedra, pose significant risks and have been banned.
  • Manuka honey is noted for safety with no known side effects.

Conclusions:

  • Manuka honey, butterbur, and Sinupret demonstrate the strongest evidence for treating allergy and AR.
  • Further research is needed to fully understand the efficacy and safety of many complementary therapies.
  • Careful consideration of risks and benefits is essential when choosing integrative treatments for AR.