What about the progress in the synthesis of flavonoid from 2020?

Flavonoids are a well-known family of natural polyphenols because of their prevalent properties in the physiological and medicinal field. In addition to a plethora of natural flavonoids, the construction of flavonoid skeletons still situates at the convergence point in the medicinal chemistry. Not surprisingly, amplification in the organic synthetic protocols showcases an expected avenue for accessing to abundant flavonoid scaffolds with special pharmacological activities. Hence, it is necessary to address the recent progresses in the synthesis of flavonoids by using organic strategies, and some typical protocols on the construction of flavonoids are thereby collected from recent publications (from 2020). The synthetic strategies presented herein are mainly cataloged as the cyclization of 4-chromanone, the glycosylation on the flavonoid scaffold, and the application of flavonoids in the pharmacological researches, aiming at providing with a current picture for depicting the recent progress on the synthesis of flavonoids. Therefore, it is expected to be a reference for the further exploration on the designing of synthetic routines for flavonoids.