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Discovery of MDV6058 (PF-06952229), a selective and potent TGFβR1 inhibitor: Design, synthesis and optimization

Brahmam Pujala1, Sreekanth A Ramachandran1, Mukesh Sonawane1

  • 1Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.

Bioorganic & Medicinal Chemistry Letters
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PubMed

Keywords:
ALK5CancerPF-06952229TGFβR1pSMAD2

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