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Levonorgestrel-Releasing Intrauterine System Utilization in Patients with Developmental Delays.

C M Lutz1, A Onwuka1, A E Lawrence2

  • 1Center for Surgical Outcomes, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.

Journal of Pediatric and Adolescent Gynecology
|September 11, 2022
PubMed
Summary

The levonorgestrel-releasing intrauterine system (LNG-IUS) is utilized for menstrual management in adolescent females with developmental delays (DDs). This study found low rates of complications, suggesting LNG-IUS is a viable option for this population.

Keywords:
Developmental delayLevonorgestrel-releasing intrauterine systemLong-acting reversible contraception

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Area of Science:

  • Reproductive Health
  • Adolescent Medicine
  • Neurodevelopmental Disorders

Background:

  • Adolescent females with developmental delays (DDs) face unique menstrual challenges.
  • Hormonal medication is often recommended for menstrual management in this population.

Purpose of the Study:

  • To describe the utilization and safety of the levonorgestrel-releasing intrauterine system (LNG-IUS) in adolescents with DDs.

Main Methods:

  • Retrospective cohort study using the Pediatric Health Information System (2011-2020).
  • Identified females aged 10-25 with DDs who underwent LNG-IUS insertion.
  • Assessed indications, complications, and early removal of LNG-IUS.

Main Results:

  • 1,560 female patients with DDs underwent LNG-IUS insertion.
  • LNG-IUS insertion under anesthesia was common in patients with autism and Down syndrome.
  • Observed low rates of perforation (1%) and mechanical complications (1%).

Conclusions:

  • This is the largest analysis of LNG-IUS use in patients with DDs.
  • Provides descriptive data for providers to counsel patients on LNG-IUS risks and benefits for menstrual management.