A Case of Pancreatic Neuroendocrine Tumor G3 Which Responded Remarkably to Chemotherapy
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Updated: Aug 29, 2025

Laparoscopic Radical Antegrade Modular Pancreatosplenectomy via Dorsal-Caudal Artery Approach for Pancreatic Neck-Body Cancer
Published on: November 18, 2022
Satoru Nebuya1, Shinji Oe1, Yoshikazu Harada2
1Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
Abstract:
Pancreatic neuroendocrine carcinoma (NEC) as classified in the World Health Organization (WHO) 2010 was reclassified in the WHO 2017 as either neuroendocrine tumor (NET) G3 or NEC. An accurate diagnosis based on the WHO 2017 classification is important in order treating this disease appropriately. We report a case diagnosed as NET G3 that responded remarkably well to treatment with streptozocin. The patient would likely not have received the streptozocin treatment if she had been diagnosed with NEC. The WHO 2017 classification is reasonable for the treatment of advanced pancreatic neuroendocrine neoplasms.
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