Standard operating procedures for biobank in oncology.

Area of Science:

• Biorepository Science
• Translational Research
• Cancer Research

Background:

• Biobanks are crucial for precision medicine and translational research, collecting and managing human biological samples and data.
• Evolving biobanking practices require updated protocols aligned with current guidelines, laws, and recommendations.
• Ensuring sample and data quality is paramount throughout the biobanking lifecycle.

Purpose of the Study:

• To illustrate the standard operating procedures (SOPs) of a certified biobank within a Cancer Center.
• To detail biobanking activities, including protocols, troubleshooting, and quality control measures.
• To support the dual mission of academic cancer centers: high-quality patient care and research.

Main Methods:

• Detailed description of biobanking activities for various biological specimens.
• Inclusion of protocols, troubleshooting guides, and quality control procedures.
• Discussion of critical methodological aspects, from informed consent to specimen management.

Main Results:

• Presentation of a comprehensive model for biobank operations within an academic Cancer Center.
• Demonstration of how biobanking integrates clinical departments and research groups.
• Identification of key challenges and solutions in specimen handling and data management.

Conclusions:

• Standardized and certified biobanking procedures are essential for reliable translational research.
• Effective biobanking supports the advancement of precision medicine in oncology.
• This model highlights best practices for biobank management in a clinical research setting.