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Related Experiment Video

Updated: Aug 29, 2025

In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments

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Neurogenic Bowel Dysfunction Over the Course of Multiple Sclerosis: A Review.

Elsie E Gulick¹

¹School of Nursing, Rutgers, The State University of New Jersey, Newark, NJ, USA (EEG).

International Journal of MS Care

|September 12, 2022

Summary

Neurogenic bowel dysfunction is a common issue for multiple sclerosis (MS) patients, affecting quality of life. This review covers causes, cofactors, and diverse management strategies for MS bowel problems.

Keywords:

management of daily activities multiple sclerosis neurogenic bowel dysfunction quality of life

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Published on: July 19, 2019

Area of Science:

Neurology
Gastroenterology

Background:

Neurogenic bowel dysfunction (NBD) is a frequent and early symptom in multiple sclerosis (MS).
NBD significantly impacts the quality of life for individuals throughout the disease course.

Purpose of the Study:

To review the causes and cofactors of NBD in MS.
To examine various management strategies for NBD in MS patients.

Main Methods:

Literature search of Medline and PubMed databases.
Review of causes, cofactors, and management options for NBD in MS.

Main Results:

NBD is influenced by factors like impaired mobility, fatigue, and psychological distress.
Management includes non-invasive methods (diet, fluids), pharmacologic treatments, and advanced therapies (biofeedback, nerve stimulation).

Conclusions:

Effective management of NBD and its cofactors is crucial for improving the quality of life in individuals with MS.
Comprehensive interventions are necessary to address the multifaceted challenges of NBD in MS.