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Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
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Metal-organic frameworks based surface-enhanced Raman spectroscopy technique for ultra-sensitive biomedical trace
Yuna Zhang1, Cuili Xue1, Yuli Xu1
1Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, 200240 China.
Nano Research
|September 12, 2022
Summary
Metal-organic frameworks (MOFs) are combined with surface-enhanced Raman scattering (SERS) to create advanced sensors. This review covers MOF synthesis for SERS substrates and their use in ultra-sensitive trace detection.
Area of Science:
- Materials Science
- Analytical Chemistry
- Nanotechnology
Background:
- Metal-organic frameworks (MOFs) offer unique microstructures and properties, driving significant research interest.
- Surface-enhanced Raman scattering (SERS) is a highly sensitive spectroscopic technique for trace detection.
Purpose of the Study:
- To summarize MOF synthesis strategies for fabricating SERS-active substrates.
- To review the applications of MOF-based SERS substrates in ultra-sensitive biomedical trace detection.
Main Methods:
- Review of literature on MOF synthesis for SERS applications.
- Analysis of studies utilizing MOF-SERS for biomedical trace detection.
Main Results:
- MOFs can be effectively synthesized into SERS-active substrates.
- MOF-SERS substrates demonstrate significant potential for ultra-sensitive biomedical detection.
Conclusions:
- Combining MOFs with SERS enhances sensing performance and broadens application scope.
- Discussion of barriers, advantages, disadvantages, and future prospects for MOF-SERS technology.
Keywords:
biomedical trace detectionmetal-organic framework (MOF)surface-enhanced Raman scattering (SERS)synthesis strategy
