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MMKP: A mind mapping knowledgebase prototyping tool for precision medicine.
Siliang Liang1, Yun Li1, Qingling Dong1
1Institute of Pharmaceutical Biotechnology and the First Affiliated Hospital Department of Radiation Oncology, Zhejiang University School of Medicine, Hangzhou, China.
Frontiers in Immunology
|September 12, 2022
Summary
A new tool, Mind Mapping Knowledgebase Prototyping (MMKP), aids precision medicine by enabling dynamic knowledge modeling. Its polymorphic foreign key design supports flexible data relationships and intuitive mind map organization for medical experts.
Area of Science:
- Biomedical Informatics
- Computational Biology
- Precision Medicine
Background:
- Precision medicine knowledge is rapidly expanding in breadth and complexity.
- Existing relational database models struggle with dynamic modeling and knowledge organization.
- These challenges hinder the potential for rapid development in precision medicine.
Purpose of the Study:
- To develop a novel tool for dynamic modeling and organization of precision medicine knowledge.
- To overcome limitations of traditional relational database models.
- To facilitate knowledge curation by medical experts.
Main Methods:
- Developed the Mind Mapping Knowledgebase Prototyping (MMKP) tool.
- Implemented a novel "polymorphic foreign key" design for flexible data linkages.
- Utilized a mind map interface for intuitive knowledge representation and curation.
Main Results:
- The MMKP tool supports dynamic changes to structural relationships in precision medicine knowledge.
- Polymorphic foreign keys enable native mind map knowledge modeling, avoiding rigid database schemas.
- The tool offers a graphical user interface for data management and knowledgebase prototyping.
Conclusions:
- MMKP significantly reduces the workload for adapting data models to evolving medical logic.
- The mind map approach facilitates a thinking-process-similar curation flow for medical experts.
- MMKP is available as open-source software, promoting accessibility and further development.
