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Leptomeningeal Metastasis Mimicking a Subacute Epidural Hematoma: Case Report
Lahfidi Amal1,2, Traore Wend-Yam Mohamed1,2, Imrani Kaoutar1,2
1Department of Radiology, Oncology National Institue, UHC Ibn Sina, Rabat, Morocco.
Abstract:
Leptomeningeal carcinomatosis is extremely rare in colorectal adenocarcinoma, its incidence is far less than 1%. The neurological symptoms are pleomorphic. The most common symptoms included Headache, ataxia, cranial nerve palsies, meningismus, focal weakness or numbness. MRI is the most sensitive and specific imaging method for screening, positive diagnosis and pre-treatment of leptomeningeal carcinomatosis. The presence of appropriate neuroimaging abnormalities in a patient with typical clinical features and history of colorectal adenocarcinoma enables to make the diagnosis of leptomeningeal metastases. As well as a biological confirmation is necessary. Treatment usually comprises site-specific radiation therapy in addition to intrathecal and systemic chemotherapy. The case aims to describe the MRI characteristics of leptomeningeal metastases so as to formulate the diagnosis and the subsequent treatment.
Insights
Leptomeningeal carcinomatosis from colorectal cancer is rare but presents with diverse neurological symptoms. Magnetic resonance imaging (MRI) is crucial for diagnosing these leptomeningeal metastases.
Area of Science:
- Neuro-oncology
- Gastroenterology
- Radiology
Background:
- Leptomeningeal carcinomatosis (LC) is a rare complication of colorectal adenocarcinoma (CRC), occurring in less than 1% of cases.
- Neurological symptoms associated with LC are varied, commonly including headache, ataxia, cranial nerve palsies, meningismus, and focal neurological deficits.
