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Case Report: Transient cortical blindness following coronary angiography
Yudi Her Oktaviono1, Maureen Victoria Kawilarang1, Michael Kawilarang1
1Departement of Cardiology and Vascular Medicine, Soetomo General and Academic Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
F1000Research
|September 13, 2022
Summary
Transient cortical blindness is a rare complication after angiography. This case shows temporary vision loss resolved spontaneously within 15 hours, suggesting contrast agent disruption of the blood-brain barrier.
Area of Science:
- Neurology
- Ophthalmology
- Radiology
Background:
- Transient cortical blindness (TCB) is an uncommon complication associated with angiography procedures.
- The exact pathophysiology of TCB following angiography remains speculative, but contrast agent-induced blood-brain barrier disruption is a likely mechanism.
Observation:
- A 52-year-old male experienced transient vision loss after undergoing coronary angiography.
- The patient's vision spontaneously returned within approximately 15 hours post-procedure.
Findings:
- Brain magnetic resonance imaging (MRI) revealed no acute pathology.
- The episode of transient vision loss resolved without specific therapeutic intervention.
Implications:
- This case highlights the possibility of TCB following coronary angiography.
- The self-resolving nature of the event suggests a temporary and reversible disruption of neurological function.

