Related Experiment Video
Updated: Aug 29, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols
Reza Shadi1, Ahmad Fakharian1, Hamid Khaloozadeh2
1Department of Electrical Engineering, Qazvin Branch, Islamic Azad University, Qazvin, Iran.
Abstract:
In this study, the extended SEIR dynamical model is formulated to investigate the spread of coronavirus disease (COVID-19) via a special focus on contact with asymptomatic and self-isolated infected individuals. Furthermore, a mathematical analysis of the model, including positivity, boundedness, and local and global stability of the disease-free and endemic equilibrium points in terms of the basic reproduction number, is presented. The sensitivity analysis indicates that reducing the disease contact rate and the transmissibility factor related to asymptomatic individuals, along with increasing the quarantine/self-isolation rate and the contact-tracing process, from the view of flattening the curve for novel coronavirus, are crucial to the reduction in disease-related deaths.
Related Concept Videos
Steps in Outbreak Investigation
Analysis of Population Pharmacokinetic Data
Statistical Methods for Analyzing Epidemiological Data
Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...
Model Approaches for Pharmacokinetic Data: Physiological Models
Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis
One important characteristic of noncompartmental analyses is that drug exposure increases proportionally with increasing doses. This...

