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A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Published on: June 18, 2018
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Cocaine Use Disorder (CUD): Current Clinical Perspectives
Elizabeth K C Schwartz1,2, Noah R Wolkowicz1,2, Joao P De Aquino1,2
1Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Substance Abuse and Rehabilitation
|September 12, 2022
Summary
Cocaine Use Disorder (CUD) treatment faces significant barriers, with no FDA-approved medications currently available. Behavioral therapies like CM and CBT-SUD show promise, but access remains a challenge for individuals with CUD.
Area of Science:
- Addiction Medicine
- Psychiatry
- Public Health
Background:
- Cocaine Use Disorder (CUD) significantly impacts individuals and society, yet treatment access is limited.
- Most individuals with CUD do not receive any form of treatment.
- Understanding risk factors, effects, and co-occurring disorders is crucial for effective intervention.
Purpose of the Study:
- To provide a comprehensive overview of Cocne Use Disorder (CUD).
- To review current and emerging treatments for CUD.
- To highlight barriers to treatment and propose a framework for treatment planning.
Main Methods:
- This is a review article.
- It synthesizes existing literature on CUD.
- It covers risk factors, effects, co-occurring conditions, and treatment modalities.
Main Results:
- No FDA-approved pharmacological treatments currently exist for CUD.
- Behavioral interventions, specifically contingency management (CM) and cognitive-behavioral therapy for substance use disorders (CBT-SUD), demonstrate efficacy.
- Individuals with co-occurring disorders may benefit from certain medications.
Conclusions:
- Despite effective behavioral interventions, significant barriers hinder treatment delivery for CUD.
- Future research should focus on larger studies and treatment combinations.
- A structured framework is needed to guide treatment planning for CUD patients.
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