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Updated: Aug 29, 2025
15:49
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
31.9K
An uncommon colonic polyp.
Margarida Gonçalves1, Joana Sobreiro Silva2, Ana Rebelo3
1Gastrenterology, Braga Hospital, Portugal.
Revista Espanola De Enfermedades Digestivas
|September 12, 2022
Summary
A colonoscopy revealed a transverse colon lesion initially diagnosed as low-grade dysplasia. Subsequent biopsies after a second colonoscopy showed no dysplasia, indicating a potential resolution or misdiagnosis of the initial finding.
Area of Science:
- Gastroenterology
- Endoscopic imaging
- Colorectal pathology
Background:
- Screening colonoscopy is crucial for detecting colorectal neoplasms.
- Early detection of dysplasia aids in preventing colorectal cancer progression.
Observation:
- A 50-year-old male presented with a 25mm exophytic transverse colon lesion with central depression.
- Initial biopsy revealed low-grade dysplasia.
- A follow-up colonoscopy showed a flat lesion with no lift-sign, precluding endoscopic resection.
Findings:
- Repeat biopsies from the flat lesion demonstrated no evidence of dysplasia.
- The initial diagnosis of low-grade dysplasia may have been transient or related to the initial lesion morphology.
Implications:
- This case highlights the importance of repeat evaluation for indeterminate colorectal lesions.
- Understanding lesion morphology changes is critical for accurate diagnosis and management.
- Further research into the natural history of such lesions may refine surveillance strategies.
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