Blood grouping with monoclonal antibodies
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The Technicon BG15 automated blood grouping machine has been used to type over 32,000 blood donors with a monoclonal anti-A and anti-B. The results of using these antibodies in parallel with conventional human antisera will be presented along with preliminary data obtained with the Groupamatic 2000 using a different anti-A. A monoclonal anti-N reagent has been assessed for its suitability for use as a blood grouping reagent in microplate assays by testing 10,000 blood donors in parallel with Vicia graminea anti-N lectin or rabbit anti-N. There was complete correlation between the results obtained with the monoclonal antibodies and conventional reagents.
The Technicon BG15 automated blood grouping machine has been used to type over 32,000 blood donors with a monoclonal anti-A and anti-B. The results of using these antibodies in parallel with conventional human antisera will be presented along with preliminary data obtained with the Groupamatic 2000 using a different anti-A. A monoclonal anti-N reagent has been assessed for its suitability for use as a blood grouping reagent in microplate assays by testing 10,000 blood donors in parallel with Vicia graminea anti-N lectin or rabbit anti-N. There was complete correlation between the results obtained with the monoclonal antibodies and conventional reagents.