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Pyrvinium doubles against WNT-driven cancer

Jiaming Fan1, Russell R Reid2, Tong-Chuan He3

  • 1Ministry of Education Key Laboratory of Diagnostic Medicine, and Department of Clinical Biochemistry, The School of Laboratory Medicine, Chongqing Medical University, Chongqing, China; Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, USA.

The Journal of Biological Chemistry
|September 12, 2022
PubMed

Keywords:
CK1α activatorE3-ubiquitin ligase component CereblonWNT-driven cancerWNT/β-catenin signalinganti-WNT agentscasein kinase 1αpyrviniumrepurposed drugs

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