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Optimising diffusion-weighted imaging of the thyroid gland using dedicated surface coil.

Y F Wang1, Y Ren1, C F Zhu1

  • 1Department of Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, 518116, China.

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Field-of-view (FOV) optimised and constrained undistorted single-shot (FOCUS) diffusion-weighted imaging (DWI) offers superior qualitative thyroid gland imaging over conventional DWI (C-DWI). However, FOCUS-DWI shows lower quantitative signal-to-noise ratio and contrast-to-noise ratio.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Diffusion-Weighted Imaging

Background:

  • Thyroid gland imaging using 3 Tesla (3T) MRI is crucial for diagnosis.
  • Conventional diffusion-weighted imaging (C-DWI) is widely used but can be limited.
  • Optimized DWI sequences are needed for improved image quality.

Purpose of the Study:

  • To evaluate the feasibility and image quality of FOCUS-DWI compared to C-DWI in the thyroid gland.
  • To assess qualitative and quantitative differences between FOCUS-DWI and C-DWI at 3T MRI.
  • To determine the potential advantages of FOCUS-DWI for thyroid imaging.

Main Methods:

  • Prospective study involving 32 healthy volunteers undergoing 3T thyroid MRI.
  • Comparison of FOCUS-DWI and C-DWI sequences.
  • Qualitative assessment by two reviewers (Likert scale) and quantitative analysis (SNR, CNR, ADC).

Main Results:

  • FOCUS-DWI demonstrated significantly better qualitative image quality, with fewer artefacts and better sharpness.
  • Quantitative analysis revealed significantly lower SNR and CNR for FOCUS-DWI compared to C-DWI.
  • Apparent diffusion coefficient (ADC) values were significantly higher with FOCUS-DWI.

Conclusions:

  • FOCUS-DWI provides superior qualitative image quality and reduced ghosting artefacts in thyroid gland MRI compared to C-DWI.
  • Despite lower quantitative SNR and CNR, FOCUS-DWI's qualitative benefits are notable.
  • Both DWI sequences have distinct advantages and can be selected based on specific clinical needs.