Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Longitudinal Research

Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...

The Effect of Aging on Tissues

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...

Aging

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

Replicative Cell Senescence

Replicative Cell Senescence

Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds...

Erikson's Theory on Socioemotional Development during Adulthood

Erikson's Theory on Socioemotional Development during Adulthood

Erik Erikson's theory of psychosocial development outlines a series of stages through which individuals progress across the lifespan. Each stage involves a psychosocial conflict that significantly influences personal growth and well-being. Three key stages — intimacy versus isolation, generativity versus stagnation, and integrity versus despair — highlight the developmental challenges faced in adulthood.
Intimacy Versus Isolation in Early Adulthood
Individuals in early...

Life Tables

Life Tables

A life table is a statistical tool that summarizes the mortality and survival patterns of a population, providing detailed insights into the likelihood of survival or death across different age intervals within a cohort. By organizing data on survival probabilities and mortality rates, life tables offer a clear snapshot of population dynamics over time. They are extensively used in demography, public health, actuarial science, and ecology to analyze life expectancy, design health interventions,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

GABA signaling activation drives glioblastoma progression in female mice through myeloid-derived suppressor cells.

Nature cancer·2026

Same author

Brain cells refine nitrogen choice with maturity.

Nature metabolism·2026

Same author

Neuronal SEL1L-HRD1 ER-associated degradation is essential for motor function and survival in mice.

The Journal of clinical investigation·2026

Same author

Past, present and future perspectives on the science of aging.

Nature aging·2026

Same author

Digital twins for in vivo metabolic flux estimations in patients with brain cancer.

Cell metabolism·2025

Same author

Adaptive nuclear GTP synthesis promotes glioblastoma treatment resistance and is a targetable vulnerability in patients.

medRxiv : the preprint server for health sciences·2025

Same journal

Optimising health care for adults with Down syndrome.

The lancet. Healthy longevity·2026

Same journal

Population-level interventions for dementia prevention: a systematic review.

The lancet. Healthy longevity·2026

Same journal

Delirium: the missing link between severe infection and subsequent dementia?

The lancet. Healthy longevity·2026

Same journal

Delirium: the missing link between severe infection and subsequent dementia?

The lancet. Healthy longevity·2026

Same journal

Conversion cascades for sensory and oral capability in primary care and community settings.

The lancet. Healthy longevity·2026

Same journal

Associations of testosterone, sex hormone-binding globulin, and related hormones with risks of cancer death, incident cancer, and incident prostate cancer in men: individual participant data meta-analyses.

The lancet. Healthy longevity·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 29, 2025

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

The longevity society.

Andrew J Scott¹

¹London Business School, Regent's Park, London, UK; Centre for Economic Policy Research, London, UK.

The Lancet. Healthy Longevity

|September 13, 2022

Summary

This summary is machine-generated.

The world is shifting from an aging society to a longevity society, focusing on how to age healthily and leverage longer lifespans. This requires rethinking social norms and public health to maximize the benefits of increased longevity for all.

More Related Videos

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae

Published on: September 17, 2020

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

Related Experiment Videos

Last Updated: Aug 29, 2025

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae

Published on: September 17, 2020

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

Area of Science:

Demography
Public Health
Gerontology

Background:

The demographic transition is evolving into a longevity transition.
Societies are moving beyond merely addressing an aging population to embracing a longevity society.
This shift necessitates a re-evaluation of population aging and its implications.

Purpose of the Study:

To define the concept of a longevity society.
To outline the necessary changes for achieving healthy longevity.
To advocate for a proactive approach to population aging.

Main Methods:

Conceptual analysis of demographic and epidemiological transitions.
Review of public health strategies for healthy aging.
Policy recommendations for a longevity society.

Main Results:

A longevity society emphasizes maximizing the advantages of longer lives through changes in aging processes.
Achieving healthy longevity requires a focus on healthy life expectancy and preventive health.
Policy changes include establishing longevity councils and intergenerational assessments.

Conclusions:

Transitioning to a longevity society requires challenging existing notions of age and aging.
Proactive public health and policy interventions are crucial for equitable healthy longevity.
Societal adaptation is needed to fully benefit from increased human lifespans.