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Two New C21 Steroidal Glycosides from Selaginella Braunii Baker
Gui-Hua Li1,2, Yan Zhang1, Jian-Ping Wu1,2
1Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, P. R. China.
Abstract:
Two new C21 steroidal glycosides, brapreguanes A and B (1-2) were isolated from 75 % aqueous ethanol extract of Selaginella braunii Baker. Their structures were established by spectroscopic analyses (1D/2D NMR spectra and HR-ESI-MS). The absolute configurations of sugar were elucidated by enzymatic hydrolysis and GCMS analysis. In addition, all compounds were evaluated for the anti-proliferative activities against various human cancer cells in vitro. Compounds exhibited no inhibition to various human cancer cells.
