Changes in plasma norepinephrine in normal labor following isometric contraction

Changes in norepinephrine following a bimanual handgrip contraction test were used to evaluate the contribution of static physical effort exerted by the parturient on the rise in adrenergic stimulation observed during ongoing labor. Noradrenaline baseline values were 306.71 +/- (SE) 21.5 pg/ml); and after a maximal effort handgrip contraction test rose to 345.07 +/- 29.11 pg/ml (p = 0.11). This increase was less pronounced than found generally in nonpregnant subjects under similar test conditions and suggests a protection of the maternal organism from excessive adrenergic output during labor.

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