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Evaluation of Patient Transmission Factor Following the Administration of 177Lu-DOTATATE
Kimyli Recca, Aeman Muneeb1, Christopher Helstern1
1Vanderbilt University Medical Center; Office of Clinical and Research Safety, A-0201 MCN, 1161 21st Avenue South, Nashville, TN 27232.
Abstract:
177Lu-DOTATATE is a radionuclide therapy that is FDA approved for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors. Treatment facilities are required to determine the maximum radiation dose from such subjects to the maximally exposed member of the public, ensuring that the total effective dose equivalent (TEDE) does not exceed regulatory limits. If the calculated TEDE meets the regulatory limits, the patient is eligible for release and provided instructions with radiation precautions. This study aims to determine a mean transmission factor to the patient to improve accuracy and individualize the estimation of the TEDE.
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