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Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
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Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line

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Pseudouridylation of Epstein-Barr virus noncoding RNA EBER2 facilitates lytic replication

Belle A Henry1, Virginie Marchand2, Brent T Schlegel1

  • 1Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15219, USA.

RNA (New York, N.Y.)
|September 13, 2022
PubMed
Summary

Epstein-Barr virus EBER2 RNA is pseudouridylated by Dyskerin, enhancing its stability and viral replication. This RNA modification is crucial for efficient Epstein-Barr virus lytic replication.

Keywords:
EBER2Epstein-Barr virusHydraPsiSeqnoncoding RNApseudouridylation

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