Tailoring Polymer-Based Nanoassemblies for Stimuli-Responsive Theranostic Applications.
Moritz S Muthwill1,2, Phally Kong1, Ionel Adrian Dinu1
1Department of Chemistry, University of Basel, Mattenstrasse 24a, BPR 1096, Basel, 4058, Switzerland.
Macromolecular Bioscience
|September 13, 2022
Summary
This review highlights advances in polymer nanoassemblies for theranostic systems, combining therapy and diagnostics. These smart systems offer enhanced efficiency for various diseases.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Polymer assemblies are crucial for developing theranostic systems, integrating therapeutic and diagnostic agents.
- Recent progress focuses on designing sophisticated polymer-based nanostructures for disease management.
Purpose of the Study:
- To review recent advances in polymer-based theranostic systems.
- To discuss the principles of polymer self-assembly for theranostic applications.
- To explore the incorporation of inorganic nanoparticles and stimuli-responsive features.
Main Methods:
- Review of literature on polymer self-assembly and supramolecular chemistry.
- Analysis of theranostic systems incorporating polymers, copolymers, and inorganic nanoparticles.
- Focus on stimuli-responsive and multicompartment nanoassemblies.
Main Results:
- Polymer nanoassemblies provide a versatile platform for theranostic applications.
- Incorporation of inorganic nanoparticles enhances multifunctionality.
- Stimuli-responsive systems demonstrate improved efficiency and targeted delivery.
Conclusions:
- Polymer-based theranostic systems offer significant advantages for treating various diseases.
- Smart nanoassemblies with tailored architectures are key for future therapeutic and diagnostic innovations.
- Further development in this field holds promise for advanced personalized medicine.
