Related Experiment Video
Updated: Aug 28, 2025

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
[Hand Osteoarthritis - Clinical Picture and Current Management]
1Kliniken Valens, Valens, Schweiz.
Hand osteoarthritis (HOA) is a common, age-related condition causing painful hand and finger dysfunction. Management prioritizes lifestyle changes and exercise, with medications and surgery considered for persistent symptoms.
Area of Science:
- Rheumatology
- Orthopedics
- Gerontology
Background:
- Hand osteoarthritis (HOA) is a prevalent, age-associated degenerative joint disease.
- It commonly affects distal finger joints, thumb carpometacarpal, proximal interphalangeal, and metacarpophalangeal joints.
- Clinical presentation includes painful functional limitations of the hand and fingers.
Purpose of the Study:
- To outline the clinical presentation of hand osteoarthritis.
- To review current management strategies for HOA.
- To discuss the efficacy of various therapeutic interventions.
Main Methods:
- Review of current literature on hand osteoarthritis.
- Analysis of clinical manifestations and etiological factors.
- Evaluation of conservative and interventional treatment options.
Main Results:
- Lifestyle modifications and exercise are primary therapeutic recommendations.
- Topical or oral non-steroidal anti-inflammatory drugs (NSAIDs) are first-line pharmacotherapy.
- Chondroitin preparations, intra-articular corticosteroids, and surgical interventions are options for refractory cases.
Conclusions:
- HOA management focuses on conservative measures, with pharmacotherapy and surgery reserved for specific indications.
- The role of laser therapy and fractionated radiation in HOA treatment remains uncertain.
- Disease-modifying drugs for inflammatory arthritis are ineffective for HOA.
Related Concept Videos
Rheumatic Heart Disease III: Medical Management
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Atherosclerosis III: Management
Rheumatic Heart Disease IV: Nursing Management
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...

