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Updated: Aug 28, 2025

Assessing Biofilm Dispersal in Murine Wounds
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Water for wound cleansing.

Ritin Fernandez1,2,3, Heidi L Green1,3, Rhonda Griffiths4

  • 1Centre for Research in Nursing and Health, St George Hospital, Kogarah, Australia.

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|September 14, 2022
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Summary
This summary is machine-generated.

This review found that using tap water for wound cleansing may have little or no effect on healing compared to no cleansing. Evidence on tap water versus saline for wound infection and healing is uncertain due to low-certainty data.

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Area of Science:

  • Wound care and management
  • Infection control
  • Evidence-based medicine

Background:

  • Normal saline is a preferred wound cleansing solution due to its isotonic properties.
  • Tap water is widely used in community settings for wound cleansing due to accessibility and cost-effectiveness.
  • The efficacy and safety of tap water for wound cleansing remain subjects of debate.

Purpose of the Study:

  • To assess the effects of different types of water for wound cleansing.
  • To compare water-based cleansing with no cleansing or other solutions like normal saline.

Main Methods:

  • Conducted a systematic review of randomized controlled trials (RCTs).
  • Searched multiple databases including Cochrane Wounds, CENTRAL, MEDLINE, Embase, and CINAHL Plus up to May 2021.
  • Included 13 RCTs involving 2504 participants with various wound types.

Main Results:

  • Cleansing with tap water showed little or no difference in wound healing compared to no cleansing (low-certainty evidence).
  • The effects of tap water, distilled water, or cooled boiled water compared to normal saline on wound infection and healing were uncertain (very low-certainty evidence).
  • Limited data were available for other outcomes such as wound size reduction, pain, and patient satisfaction.

Conclusions:

  • The current evidence, all of low or very low certainty, suggests tap water may not significantly impact wound healing compared to no cleansing.
  • There is insufficient evidence to determine the effects of tap water, distilled water, or cooled boiled water compared to saline for wound cleansing.
  • Further high-quality research is needed to clarify the role of different water types in wound care.