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Dissemination in cutaneous leishmaniasis. I. Subcutaneous nodules
International Journal of Dermatology
|June 1, 1987
Summary
Subcutaneous nodules (SCN) in cutaneous leishmaniasis (CL) patients, often near primary lesions, suggest lymphatic spread. This phenomenon, observed in 10% of Saudi Arabian patients, may be treatment-induced.
Area of Science:
- Dermatology
- Infectious Diseases
- Parasitology
Background:
- Cutaneous leishmaniasis (CL) is a parasitic skin infection.
- Lymphatic dissemination is a recognized complication of some infectious diseases.
Purpose of the Study:
- To investigate the occurrence and characteristics of subcutaneous nodules (SCN) in patients with CL.
- To determine if SCN represent lymphatic spread of Leishmania major.
Main Methods:
- Clinical observation of CL patients in Saudi Arabia.
- Pathological examination of subcutaneous nodules.
Main Results:
- 10% of CL patients presented with SCN.
- SCNs were typically painless, proximal to primary lesions, and sometimes exhibited a sporotrichoid or beaded cord pattern.
- The number of SCNs ranged from 1-16, averaging 3.25.
- Antileishmanial treatment appeared to trigger SCN development in some cases.
Conclusions:
- SCNs in CL patients are likely a manifestation of lymphatic dissemination.
- This form of lymphatic spread in CL is not widely recognized.