Benzydamine, an unique model of anti-inflammatory activity

Benzydamine is an anti-inflammatory drug with unique medical uses, namely the topical treatment of oro-pharyngeal and gynaecological conditions. This paper illustrates the rationale for the medical use of benzydamine. Its differences from aspirin-like drugs are pointed out, and evidence is presented that benzydamine does not primarily affect the PGs system, but rather reduces the cell response to injury.