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Updated: Aug 28, 2025

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Diffuse arterial embolization secondary to pulmonary vein thrombosis
Keegan Plowman1, Carl Ruthman2
1Graduate Medical Education Internal Medicine Residency, NCH Healthcare System, 311 9th Street North, Naples, FL, 34102, USA.
Pulmonary vein thromboses (PVT) is a serious complication of lung cancer, potentially leading to arterial emboli. This case highlights PVT in a patient with lung mass, resulting in widespread organ infarction.
Area of Science:
- Cardiovascular Medicine
- Oncology
- Radiology
Background:
- Pulmonary vein thromboses (PVT) can arise as a complication of lung malignancy.
- PVT may lead to arterial embolic events, causing significant morbidity.
Observation:
- A 69-year-old female with coronary artery disease and pneumonia presented with neurological and abdominal symptoms.
- Imaging revealed bilateral strokes, renal infarction, and splenic infarction.
- A right upper lobe lung mass was identified, compressing the pulmonary veins and showing signs of thrombus.
Findings:
- CT angiogram, echocardiogram, and MRI confirmed PVT.
- The lung mass was the likely cause of the pulmonary vein compression and thrombus formation.
Implications:
- This case underscores the critical link between lung malignancy, PVT, and systemic arterial embolism.
- Prompt diagnosis and anticoagulation are crucial for managing PVT and preventing further embolic events.
- Treatment should address both the thrombosis and the underlying malignancy.
Related Concept Videos
Pulmonary Embolism I: Introduction
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism III: Nursing Management
Venous Thrombosis I: Introduction
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

