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Coronavirus (COVID-19) infection - impact on cardiovascular system

Mariam Ahmed1, Patrick Anthony Ball1, Hana Morrissey1

  • 1School of Pharmacy, Faculty of Science and Engineering, University of Wolverhampton, United Kingdom.

Medicine and Pharmacy Reports
|September 15, 2022
PubMed

Insights

COVID-19 infection significantly impacts the cardiovascular system, increasing mortality risk, especially in patients with pre-existing heart conditions. Primary care providers must monitor evolving evidence for optimal patient management.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Coronaviruses, including SARS-CoV-2 causing COVID-19, are RNA viruses impacting multiple organ systems.
  • Cardiovascular complications are a significant concern in COVID-19 patients.
  • Myocardial injury is strongly associated with increased mortality in COVID-19.

Purpose of the Study:

  • To review the impact of COVID-19 on the cardiovascular system.
  • To outline patient management strategies in primary and community care settings.

Main Methods:

  • A literature search and review of published papers from 2020.
  • Focus on studies concerning Coronaviruses and cardiovascular disease.

Main Results:

  • Myocardial injury is a key factor in COVID-19 mortality.
  • Patients with underlying cardiovascular diseases face a worse prognosis.
  • Inflammation is a potential mechanism for cardiac injury in COVID-19.

Conclusions:

  • Aggressive COVID-19 treatment is recommended for patients with cardiovascular diseases.
  • Primary care practitioners must stay updated on emerging evidence for managing at-risk patients.
  • Continued monitoring of evolving research is crucial for understanding COVID-19's cardiovascular impact.
Abstract

Keywords:
COVID-19Coronavirus (SARS-CoV-2)Inflammatory responseMyocardial injuryangiotensin converting enzyme 2 (ACE2)

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