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Updated: Aug 28, 2025
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Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
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The ethical case for placebo control in HIV-cure-related studies with ART interruption
Monica Magalhaes1, Daniel R Kuritzkes2,3, Nir Eyal1,4,5
1Center for Population-Level Bioethics, Rutgers University, New Brunswick, NJ, USA.
Journal of Virus Eradication
|September 15, 2022
Abstract:
Many studies that seek to cure HIV must ask participants to interrupt their antiretroviral treatment. In such circumstances, is it permissible to include a placebo group in the study? We explain why doing so is a scientific and an ethical necessity, and more benign than imagined.
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