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Tuberculosis-Associated Anemia: A Narrative Review
Thejaswi Dasaradhan1, Jancy Koneti2, Revanth Kalluru2
1Research, Narayana Medical College, Nellore, IND.
Cureus
|September 15, 2022
Summary
Tuberculosis (TB) is an airborne illness often linked with anemia. This review explores how TB causes anemia, identifies risk factors, and evaluates treatments like iron therapy for TB-associated anemia.
Area of Science:
- Infectious Diseases
- Hematology
- Immunology
Background:
- Tuberculosis (TB) is an airborne infectious disease primarily affecting the lungs.
- Anemia is a frequent comorbidity in TB patients, complicating disease management.
- Systemic inflammation and cytokine dysregulation are hallmarks of TB.
Purpose of the Study:
- To elucidate the pathogenesis of anemia in TB patients.
- To identify risk factors associated with developing anemia in TB.
- To review and assess the efficacy of therapeutic interventions for TB-associated anemia.
Main Methods:
- Comprehensive literature review of studies on TB and anemia.
- Analysis of the role of cytokines in anemia development during TB.
- Evaluation of therapeutic strategies including antitubercular and iron therapy.
Main Results:
- Cytokines play a significant role in the pathogenesis of anemia in TB.
- Specific risk factors increase the likelihood of anemia in TB patients.
- Antitubercular therapy and iron supplementation show varying efficacy in managing anemia.
Conclusions:
- Understanding TB-induced anemia requires examining pathogenesis and cytokine involvement.
- Identifying risk factors aids in proactive anemia management for TB patients.
- Hepcidin and ferritin measurements are crucial for assessing and managing anemia in TB.
Keywords:
anemiaanemia of chronic diseasesantitubercular therapy (att)cytokinesferritinhepcidiniron therapytuberculosisMore Related Videos
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