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Effect of the COVID-19 Pandemic on Treatment Adherence Among Children With Congenital Adrenal Hyperplasia

Samahir A Alsulaimani1, Ahlam Mazi1, Mohammed Bawazier2

  • 1Pediatric Department, King Abdulaziz University, Jeddah, SAU.

Cureus
|September 15, 2022
PubMed

Insights

The COVID-19 pandemic had a minimal impact on medication adherence for children with congenital adrenal hyperplasia (CAH) in Jeddah. Challenges with medication access persisted but did not significantly alter adherence rates.

Area of Science:

  • Pediatric Endocrinology
  • Public Health
  • Genetics

Background:

  • Congenital Adrenal Hyperplasia (CAH) requires consistent medication adherence for management.
  • The COVID-19 pandemic presented unprecedented challenges to healthcare access and supply chains globally.
  • Understanding the pandemic's impact on chronic condition management in pediatric populations is crucial.

Purpose of the Study:

  • To evaluate the effect of the COVID-19 pandemic on medication adherence in pediatric patients with CAH.
  • To identify factors influencing adherence during the pandemic in the Kingdom of Saudi Arabia (KSA).

Main Methods:

  • Prospective data collection from April 2020 to April 2022.
  • Interviews conducted via face-to-face or telephonic methods at a virtual pediatric endocrine clinic in Jeddah, KSA.
  • Inclusion of 55 children diagnosed with CAH.

Main Results:

  • Medication adherence remained high, with 93% before and 89% during the pandemic (p=0.516).
  • Primary non-adherence reasons included restricted medication access (supply/financial) and prescription refill difficulties, which worsened during the pandemic.
  • Maternal education level correlated with medication administration, unlike paternal education.

Conclusions:

  • The COVID-19 pandemic did not significantly alter medication adherence rates in children with CAH in Jeddah.
  • Challenges in accessing medication supply and refills were exacerbated by the pandemic but did not lead to a significant decrease in adherence.
  • Healthcare providers should continue to monitor and address medication access issues for pediatric patients with chronic conditions.
Abstract

Keywords:
cah treatment compliancecovid-19 and cahcovid-19 pandemic and cah treatmenteffect of covid-19 on cahimpact of covid-19 on treatmentlockdown and cah treatment compliance

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