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Related Experiment Video

Updated: Aug 28, 2025

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
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Targeted temperature management evolving over time-A local process analysis.

Axel Strålin1, Meena Thuccani1, Linus Lilja1

  • 1Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.

Acta Anaesthesiologica Scandinavica
|September 15, 2022
PubMed
Summary

Target temperature management (TTM) quality improved over time in cardiac arrest survivors. Increased experience with TTM protocols led to better precision in achieving target temperatures and reduced fever incidence, supporting standardized care.

Keywords:
feverhypothermiaintensive careout-of-hospital cardiac arrestpost-resuscitationprecisionqualitytargeted temperature managementtemperaturetime to target

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Area of Science:

  • Critical Care Medicine
  • Neurology
  • Cardiology

Background:

  • Post-resuscitation care for cardiac arrest survivors includes target temperature management (TTM) to minimize brain injury.
  • High-quality TTM necessitates precise protocols.
  • This study investigates TTM quality evolution with clinical experience.

Purpose of the Study:

  • To assess the impact of increasing experience and evolving protocols on TTM quality.
  • To determine if TTM quality improved between clinical trial periods and current practice.

Main Methods:

  • Defined TTM quality by time to target, temperature variability, and fever incidence.
  • Analyzed data from 181 patients across three periods (2011-2021) with varying TTM protocols.
  • Compared TTM quality between groups with similar target temperatures.

Main Results:

  • TTM quality significantly improved across all measured parameters between trial periods.
  • No significant difference in temperature variability or fever incidence between later protocols (<37.5°C and 36°C).
  • A 33°C target temperature showed lower fever incidence compared to 36°C and <37.5°C targets.

Conclusions:

  • Increased TTM quality likely stems from enhanced competence through learning and training in strict protocols.
  • Findings support the protocolization of post-cardiac arrest intensive care for improved outcomes.