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Published on: May 20, 2019
Ni-catalyzed C-S bond construction and cleavage
Su Huang1, Ming Wang1, Xuefeng Jiang1
1Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China. xfjiang@chem.ecnu.edu.cn.
Nickel catalysis enables efficient synthesis and modification of sulfur compounds like sulfides and disulfides. This review highlights key nickel-catalyzed cross-coupling strategies for diverse sulfur-containing molecules.
Area of Science:
- Organic Chemistry
- Catalysis
- Materials Science
Background:
- Sulfur compounds are vital in pharmaceuticals, agriculture, and materials.
- Efficient synthesis methods for sulfur compounds are crucial.
- Nickel catalysis offers a cost-effective and versatile approach.
Purpose of the Study:
- To review nickel-catalyzed methods for constructing and transforming sulfur-containing compounds.
- To cover sulfides, disulfides, and hypervalent sulfur compounds.
- To emphasize the role of nickel in sulfur chemistry.
Main Methods:
- Focus on nickel-catalyzed cross-coupling reactions.
- Discussion of various sulfur-containing substrates.
- Highlighting reaction mechanisms and efficiency.
Main Results:
- Nickel catalysis facilitates diverse sulfur compound synthesis.
- Effective transformations of sulfides, disulfides, and hypervalent sulfur compounds.
- Demonstration of nickel's catalytic activity and versatility.
Conclusions:
- Nickel-catalyzed cross-coupling is a powerful strategy for sulfur chemistry.
- This review provides a comprehensive overview of recent advancements.
- Future directions in nickel-catalyzed sulfur compound synthesis.
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