A guide to open science practices for animal research

Area of Science:

• Biomedical Research
• Translational Science
• Scientific Publishing

Background:

• Translational biomedical research uses animal experiments as foundational evidence for clinical trials.
• There is a critical need for researchers to maximize experimental output due to the inherent duty of care.
• Open science practices offer potential to improve research transparency, quality, and reach.

Purpose of the Study:

• To provide a practical guide for implementing open science practices throughout the research lifecycle.
• To enhance the transparency and quality of translational research.
• To increase the audience and scientific reach of published research.

Main Methods:

• The essay outlines open science applications from study design to publication and dissemination.
• It includes a continuously updated online toolbox of resources for practical implementation.
• Focuses on actionable strategies for researchers.

Main Results:

• Open science implementation can significantly improve the rigor and reproducibility of translational studies.
• Practical application of open science principles can lead to broader dissemination and impact of research findings.
• The provided resources aim to facilitate the adoption of open science in daily research workflows.

Conclusions:

• Adoption of open science practices is crucial for advancing translational biomedical research.
• A structured approach to open science enhances research quality and impact.
• Continuous access to updated resources supports the evolving landscape of open science.