Incidence and Predictive Factors Associated With Delayed Extubation After Pediatric Neurosurgery

Decisions on appropriate time of extubation after pediatric neurosurgery are often challenging for anesthesiologists. The primary goal was to investigate the incidence of delayed extubation after pediatric neurosurgery. The secondary goal was to identify the factors affecting delayed extubation in these patients.

This retrospective study was done in pediatric patients who underwent neurosurgery at a university hospital in a 5-year period from April 2015 to March 2020. Delayed extubation was that the patients who were not extubated at the end of procedure before leaving the operating room. Demographic data, preoperative and intraoperative factors associated with delayed extubation were collected and analyzed.

A total of 539 pediatric patients were included in our study. There were 56 children in delayed extubation group with the incidence of 10.4%. In the multivariate analysis, the factors associated with delayed extubation were including neonates (adjusted odds ratio [aOR], 3.743; 95% confidence interval [CI], 1.076-13.028), American Society of Anesthesiologists physical status III-IV (aOR, 3.010; 95% CI, 1.057-8.573), preoperative oxygen supplement (aOR, 6.033; 95% CI, 1.713-21.243), intracranial surgery (aOR, 4.494; 95% CI, 1.458-13.847), estimated blood loss (EBL) ≥ 40% of total blood volume (TBV) (aOR, 5.465; 95% CI, 1.640-18.210), and finishing operation after official hours (aOR, 3.810; 95% CI, 1.633-8.889).

There were the preoperative and intraoperative factors associated with delayed extubation such as preoperative oxygen supplement, intracranial surgery, or EBL ≥ 40% of TBV. These might be useful for anesthesiologists in making decisions about the planning of extubation after neurosurgery in children.